This original piece of art by the artist Logans Art is called Loyalty Never Dies. It depicts Dogmeat and a Female Vault Dweller defending each other against a charging Deathclaw.
Every print comes with a stamped paw print taken from a silicone cast of my own German Shepherd Dog Furi's paw.
Size is A4, 220mm x 290mm printed on 240 Gr./Gsm. Glossy Photo Paper.